VASOPRESSIN

 

Class: Pituitary hormone

 

Mechanism of Action: Contraction of smooth muscles of GI tract and all parts of vascular bed;  increased absorption of water by renal tubules giving antidiuretic action.

 

Indications: Prevention and treatment of postoperative abdominal distention;  Diabetes insipidus

 

Contraindications: Hypersensitivity

 

Precautions: Vascular disease, may produce water intoxication

 

Side Effect: Cardiac arrest, decreased cardiac output, abdominal cramps, nausea/vomiting

 

Dosage: 5-10 units (0.25-0.5ml) IM,SQ